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Resolve Chronic Inflammation and Achieve Healthy Ageing by Understanding Non-regenerative Repair


Paolo Madeddu

Prof, MD, CS, FAHA, Head of Division


  • Murine models of skin ischemic wounds, limb ischemia, myocardial infarct, atherosclerosis
  • Reparative angiogenesis
  • Role of the p75NTR receptor for neurotrophins in fibrotic wound healing
  • Apoptosis
  • Endothelial cell biology
  • Bone marrow cell biology
  • Genetically modified murine models

For more information see personal website

Work Contribution within RESOLVE

Prof. Madeddu coordinates clinical studies on models of healing, his team concentrate on research aiming at dissecting the impact of diabetes and aging on the repair mechanisms (temporal and context specific).

Working Group

Dr. Rajeshi Katare, MD, PhD, Research Fellow
Dr. Nicolle Kraenkel, PhD Research Fellow
Dr. Atsuiko Oikawa. PhD, Research Assistant


Bristol Heart Institute
University of Bristol
Bristol Royal Infirmary, level 7
Upper Maudlin Road
BS2 8HW  Bristol, United Kingdom

Phone  +44 117 928 3904
Fax +44 117 928 3904
Skype paolomadeddu