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Resolve Chronic Inflammation and Achieve Healthy Ageing by Understanding Non-regenerative Repair

Data analysis by high throughput techniques

RESOLVE utilizes systems biology to capture gene functions related to inflammatory and fibroproliferative repair. Its sequence of models assessing different modalities of organ repair in animals, human diseases and in vitro cultures allows for the evaluation of:

  • Quality of repair
  • Involvement of organ developmenta
  • Age-dependency
  • Influence of experimental treatment


Resolve performs:

  • Genome-wide gene expression analysis
  • Quantitative Proteomics
  • Micro RNA expression profiling
  • DNA methylation profiling
  • Toponomics, Immunochemistry and
  • Evaluation of single mechanisms by cell biology


Christa Nöhammer
(Austrian Research Centers) - workpackage-leader

Marco Chilosi (University of Verona)
Almut Nebel (Christian-Albrechts-Universität)